Cheesy beef casserole is a hearty one-dish dinner that combines browned ground beef, tender pasta, and a rich tomato sauce under a blanket of melted cheese. It is easy to prep, bakes in one pan, and works perfectly for busy weeknights or meal prep.

This recipe is ideal when you want comfort food without a long ingredient list. If you like easy baked dinners, compare this to our chicken broccoli rice casserole on a night when you want a lighter option.
Recipe Snapshot
- Prep time: 20 minutes
- Cook time: 30 minutes
- Yield: 6 to 8 servings
- Best for: weeknight dinners, meal prep, potlucks
- Texture: saucy pasta with tender beef and cheesy top
Why This Recipe Works
Browning the beef first builds flavor, while simmering the tomato sauce lets the seasonings meld before the pasta goes in. Combining everything in one dish keeps cleanup simple.
A blend of cheddar and mozzarella gives you both sharp flavor and stretchy melt. For another cozy cheese-forward bake, try our crock pot mac and cheese.
Ingredients

- 1 lb ground beef
- 1 medium onion, diced
- 2 cloves garlic, minced
- 1 can (15 oz) tomato sauce
- 1 can (14.5 oz) diced tomatoes, drained
- 1 teaspoon Italian seasoning
- 1/2 teaspoon kosher salt
- 1/4 teaspoon black pepper
- 2 cups cooked pasta, penne or rotini
- 1 1/2 cups shredded cheddar cheese
- 1/2 cup shredded mozzarella cheese
- Fresh parsley, chopped, optional for garnish
How to Make Cheesy Beef Casserole
1. Preheat and prep the dish
Preheat the oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish.
2. Brown the beef
Cook the ground beef in a large skillet over medium heat until browned. Drain excess fat, then add onion and garlic and cook until softened.

3. Simmer the sauce
Stir in the tomato sauce, diced tomatoes, Italian seasoning, salt, and pepper. Simmer for 10 minutes until the flavors come together.

4. Combine with pasta
Stir the cooked pasta into the beef mixture until evenly coated.

5. Assemble and bake
Transfer the mixture to the prepared baking dish. Top with cheddar and mozzarella, then bake for 20 minutes until bubbly and golden.

6. Rest and serve
Let the casserole rest for 5 minutes, then garnish with parsley if desired and serve.

Tips for the Best Beef Casserole
- Drain the beef well so the casserole does not turn greasy.
- Cook pasta al dente since it bakes again in the oven.
- Season the sauce before adding cheese.
- Use freshly shredded cheese for better melting.
- Let the dish rest before serving for cleaner scoops.
Variations
Add bell peppers, mushrooms, or spinach for extra vegetables. Use ground turkey for a leaner version. Swap in pepper jack for a spicier finish. For another make-ahead option, browse our 7 easy make-ahead dinners to simplify your week.
Serving Ideas
- Serve with garlic bread and a green salad.
- Pair with roasted vegetables for a fuller plate.
- Pack leftovers into meal prep containers.
- Top with extra parsley or red pepper flakes.
- Serve with steamed broccoli on the side.
Storage and Reheating
Store leftovers in an airtight container for up to 4 days in the refrigerator. Reheat covered at 350°F for 15 to 20 minutes, or microwave individual portions until hot.
Make-Ahead Checklist
- Cook the pasta while the beef sauce simmers.
- Drain browned beef well before adding vegetables.
- Taste and adjust seasoning before assembling.
- Grease the baking dish before transferring the mixture.
- Add cheese just before the final bake.
- Rest 5 minutes after baking for easier serving.
Frequently Asked Questions
Can I make this casserole ahead of time?
Yes. Assemble the casserole, cover, and refrigerate for up to 24 hours before baking. Add a few extra minutes to the bake time.
Can I freeze cheesy beef casserole?
Yes. Bake, cool completely, then freeze in a sealed container for up to 2 months. Thaw overnight and reheat covered in the oven.
What pasta works best?
Penne, rotini, and rigatoni all work well because they hold the sauce in every bite.
Can I use lean ground beef?
Yes. Lean ground beef works fine, but drain any excess liquid after browning.
Why is my casserole dry?
The sauce may have reduced too much or the pasta absorbed too much liquid. Add a splash of broth before baking if needed.
Can I make it spicier?
Yes. Add red pepper flakes, hot sauce, or pepper jack cheese for heat.
Can I double the recipe?
Yes. Use a larger baking dish and increase the bake time by 5 to 10 minutes as needed.
Final Thoughts
Cheesy beef casserole is a reliable comfort dinner that comes together with simple pantry ingredients. Brown the beef well, simmer the sauce, and bake until the cheese turns golden. For another hearty loaded bake, try our cheesy loaded chicken potato bake.